thyroid hormone receptor(thr) — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40548	NH-3		Thyroid hormone receptor(THR)
	NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...		Thyroid hormone receptor(THR)
T5360	Eprotirome	KB2115	Thyroid hormone receptor(THR)
	Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.		Thyroid hormone receptor(THR)
T1604	Tiratricol	3,3',5-Triiodothyroacetic acid	Thyroid hormone receptor(THR)
	Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A...		Thyroid hormone receptor(THR)
T13072	Taltirelin acetate	TA-0910 acetate	Thyroid hormone receptor(THR)
	Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).		Thyroid hormone receptor(THR)
T3595	Resmetirom	VIA-3196,MGL3196	Thyroid hormone receptor(THR)
	Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.		Thyroid hormone receptor(THR)
T6956	Protirelin	Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T5313	Sobetirome	IACS-010759,QRX-431	Thyroid hormone receptor(THR)
	Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).		Thyroid hormone receptor(THR)
T13492	3,5-Diiodothyropropionic acid	C082182,Ditpa cpd	Thyroid hormone receptor(THR)
	3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).		Thyroid hormone receptor(THR)
T7578	REVERSE T3	3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)
	Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.		Thyroid hormone receptor(THR)
TP1022	Protirelin Acetate	TSH-RF Acetate,TRH Acetate,TRF Acetate	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T0864	L-Thyroxine	Levothyroxine,NSC 36397,T4	Thyroid hormone receptor(THR) , Endogenous Metabolite
	L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...		Thyroid hormone receptor(THR) , Endogenous Metabolite
T1669	Liothyronine sodium	3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel	Thyroid hormone receptor(THR)
	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s...		Thyroid hormone receptor(THR)
T22355	L-Thyroxine sodium	LT4 sodium,Levothyroxine sodium,L-T4 sodium	Thyroid hormone receptor(THR)
	L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.		Thyroid hormone receptor(THR)
T1653	Liothyronine	Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)
T7590	Taltirelin	TA-0910	Thyroid hormone receptor(THR)
	Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].		Thyroid hormone receptor(THR)
T15699	L-Thyroxine sodium salt pentahydrate	Sodium levothyroxine pentahydrate,Levothyroxine	Thyroid hormone receptor(THR)
	L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxi...		Thyroid hormone receptor(THR)
T79089	THR-β modulator-1
	THR-β Modulator-1 (Compound 1a) is a potent modulator of the thyroid hormone receptor β, utilized in the study of thyroid hormone receptor-associated disorders [1].
T74785	THR-β agonist 6
	THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remar...